The Urology Clinic - Georgia Lithotripsy & Laser Center logo for print

120 Trinity Place
Athens, GA 30607

Phone: (706) 543-2718
Fax: (706) 353-3709

120 Trinity Place
Athens, Georgia 30607

(706) 543-2718

Prostate Biopsy

Prostate biopsy is a procedure performed to rule out prostate cancer. The only means of diagnosing prostate cancer is with a biopsy of the prostate. However, since only a portion of the prostate is sampled, it is possible that a biopsy can miss a cancer.


  • Elevated PSA
  • Abnormal digital rectal examination


Two hours before the procedure, the patient uses an enema to clean the rectum. During the procedure, the patient lies on an exam table, and an ultrasound probe is placed into the rectum. The prostate is then imaged and measured, and a local anesthetic is then injected at the base of the prostate to provide a nerve block. Most patients will sense the probe in their rectum, but should not experience pain during the biopsy. Once the anesthetic has been given, specimens are taken from select locations in the prostate with a specialized biopsy needle. The entire procedure takes about ten minutes, and the patient is able to go home a few minutes after it is completed. It is important that patients bring a driver with them to the procedure. The biopsy results usually are back in about five to seven business days.

It is very important that the patient stop taking aspirin or other blood thinners 7 days prior to the procedure.

Patients should follow the prostate biopsy instructions prior to this procedure.

Side Effects

Patients may experience some discomfort when the probe is placed even though the probe does not go any farther than when a doctor performs a rectal exam. Almost all patients will see blood or dark streaks in their ejaculate after biopsy, and this may take several weeks to clear entirely. Many patients will see some blood in their bowel movements or even urine after prostate biopsy, which usually clears up in a few days. On occasion, a patient may have some difficulty urinating after biopsy. Patients are given antibiotics before and after the procedure, but on very rare occasion may develop infection, a fever (>101°), or increased pain in the pelvis. Should this happen, please contact us immediately.